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Pharmacological Studies On A Coastal Sand Dune Plant Citrullus Colocynthis (l) Shard: Antidiabetic And Anti Oxidant Activities In Albino Rats  


Abstract Category: Science
Course / Degree: M.Sc.
Institution / University: Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, India
Published in: 2008


Dissertation Abstract / Summary:

The present investigation evaluate the antidiabetic effect of Citrullus colocynthis on liver hexokinase and gluconeogenic enzymes such as glucose-6-phosphatase and fructose 1, 6-bisphosphatase in the liver of control and alloxan-diabetic rats. Oral administration of leaf suspension of Citrullus colocynthis (250mg and 500mg /kg body weight) for 60 days resulted in momentous reduction in blood glucose (from 381 ± 34 to 105 ± 35), glycosylated hemoglobin, a decrease in the activities of glucose-6 phosphatase and fructose 1, 6-bisphosphatase, and an increase in the activity of liver hexokinase. The enzymatic antioxidants such as catalase, super oxide dismutase, glutathaione reductase, glutathaione reductase and glutathiaone-S- transferase and non enzymic antioxidant (ascorbic acid, ά- tocoperol, reduced glutathiaone, total carotenoids and flavonoids) were found to be present. The result obtained in the present study indicated that the coastal medicinal plant Citrullus colocynthis might be a good source of natural antidiabetic and antioxidant source.


Dissertation Keywords/Search Tags:
Citrullus colocynthis, diabetes

This Dissertation Abstract may be cited as follows:
Gurudeeban S., 2008.Pharmacological studies on a Coastal sand dune plant Citrullus colocynthis (L) Shard: Antidiabetic and anti oxidant activities in albino rats, (Research Guide: Dr.T.Ramanathan)

Dissertation Images:
Science - Pharmacological Studies On A Coastal Sand Dune Plant Citrullus Colocynthis (l) Shard: Antidiabetic And Anti Oxidant Activities In Albino Rats Citrullus colocynthis
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Submission Details: Dissertation Abstract submitted by Gurudeeban Selvaraj from India on 02-Feb-2013 19:45.
Abstract has been viewed 2636 times (since 7 Mar 2010).

Gurudeeban Selvaraj Contact Details: Email: gurudeeb99@gmail.com



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